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Prestone 50/50 Prediluted Antifreeze-Coolant, Formulated for Toyota Vehicles, AF6200-08/01/2018
Products in this Consumer Product Information Database (CPID) are classified based on their composition:
Substances: single chemicals
Preparations: products which contain chemicals that can be easily separated during normal use
Articles: products or product assemblies that do not contain chemicals that can be separated out from the product or assembly under normal or advertised use.
Classification: Preparation
Indicates country where product is sold.
Market: US/CanadaPurpose of product.
Usage: Automobile radiator fluid.Structure such as solid, liquid, aerosol etc.
Form: liquidDate when validity of Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) was last verified.
Date verified: April 24, 202569 Eagle Road
Danbury CT 06810
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Chemical Composition/Ingredients
The GHS is an acronym for The Globally Harmonized System of Classification and Labelling of Chemicals. The GHS is a system for standardizing and harmonizing the classification and labelling of chemicals. Chemicals are associated with codes that define their health, physical and environmental hazards.This universal hazard communication system was developed to ensure that employers, employees and consumers are provided with adequate, practical, reliable and comprehensible information on the hazards of chemicals, so that they can take effective preventive and protective measure for their own health and safety.
Advanced
The GHS classifications for chemicals associated with products in this database may be viewed by selecting the "Advanced" button on the Chemical Ingredients tables. Since this is a work in progress, GHS classifications may not be shown for all chemical ingredients.-
Primary Chemical Name is the standard name assigned to a chemical substance.
ChemicalChemical Abstracts Service Registry Number is a unique identifier for a chemical and its synonyms. CAS numbers identify the chemical, but not its concentration or specific mixture. CAS Registry Numbers are assigned by the Chemical Abstracts Service, a division of the American Chemical Society. For more information: www.cas.org
CAS No./ID
We have assigned "ID numbers" (with 6 leading zeros or nines, e.g., 000000-xx-x , 888888-xx-x) or 999999-xx-x) for blends and chemicals that do not have CAS numbers.Percent of chemical in preparation.
% Conc.Chemical of Concern (CoC)
Chemical of Concern(CoC)Ethylene glycol 000107-21-1 30.0-60.0 Yes 
CoC List
Water 007732-18-5 30.0-60.0 No Diethylene glycol 000111-46-6 0-5.0 No Hexanoic acid, 2-ethyl-, sodium salt (1:1) 019766-89-3 1.0-5.0 No -
Health Effects Information
Ingredients and Health Effects Information are taken from the manufacturer's product label and/or the Safety Data Sheet (SDS). Products are not tested and manufacturer's information presented here is not evaluated by DeLima Associates.
View Safety Data Sheet(SDS) Date that the Safety Data Sheet (SDS) was issued by manufacturer of a specific product.
SDS DATE :August 01, 2018 Health Flammability Reactivity HMIS is the Hazardous Materials Identification System developed by the American Coatings Association and indicates the levels (“1” to “4”) of Health Hazard, Flammability Hazard and Physical Hazard associated with a specific product.
HMIS RATING1 2 0 Measure of Alkalinity/Acidity of substance or preparation where a level of 7 is considered as neutral.
pH Levels8.3 -
Warnings
Hazard Statements
Warning. Harmful if swallowed. Suspected of damaging the unborn child. May cause damage to kidneys through prolonged or repeated exposure.
Precautionary Statements
General
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood.
Prevention
Do not breathe mist or vapors. Wash exposed skin thoroughly after handling. Do not eat, drink, or smoke when using this product. Wear protective gloves and eye protection.
Response
IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell. Rinse mouth.
IF exposed or concerned: Get medical advice.
Storage
Store locked up.
Disposal
Dispose of contents and container in accordance with local and national regulations. -
Acute health effects
From SDS:
Hazards Identification
Emergency Overview
Warning. Harmful if swallowed. Suspected of damaging the unborn child. May cause damage to kidneys through prolonged or repeated exposure.
Potential Health Effects
Eye Contact: Liquid, vapors or mist may cause discomfort in the eye with persistent conjunctivitis, seen as slight excess redness or conjunctiva. Serious corneal injury is not anticipated.
Skin Contact: No evidence of adverse effects from available information.
Inhalation: May cause irritation of the nose and throat with headache, particularly from mists. High vapor concentrations caused, for example, by heating the material in an enclosed and poorly ventilated workplace, may produce nausea, vomiting, headache, dizziness and irregular eye movement.
Ingestion: May cause abdominal discomfort or pain, nausea, vomiting, dizziness, drowsiness, malaise, blurring of vision, irritability, back pain, decrease in urine output, kidney failure, and central nervous system effects, including irregular eye movements, convulsions and coma. Cardiac failure and pulmonary edema may develop. Severe kidney damage which may be fatal may follow the swallowing of ethylene glycol. A few reports have been published describing the development of weakness of the facial muscles, diminishing hearing, and difficulty with swallowing, during the late stages of severe poisoning. -
Chronic health effects
From SDS:
Prolonged or repeated inhalation exposure may produce signs of central nervous system involvement, particularly dizziness and jerking eye movements. Prolonged or repeated skin contact may cause skin sensitization and an associated dermatitis in some individuals. Ethylene glycol has been found to cause birth defects in laboratory animals. The significance of this finding to humans has not been determined. 2-Ethyl Hexanoic Acid, Sodium Salt is suspected of causing developmental effects based on animal data. -
Carcinogenicity
None of the components of these products is listed as a carcinogen or suspected carcinogen by IARC, NTP, ACGIH, or OSHA. -
Handling information
Harmful or Fatal if Swallowed. Do not drink antifreeze or solution. Avoid eye and prolonged or repeated skin contact. Avoid breathing vapors or mists. Wash exposed skin thoroughly with soap and water after use. Do not store in opened or unlabeled containers. Keep container away from open flames and excessive heat. Do not reuse empty containers unless properly cleaned. Empty containers retain product residue and may be dangerous. Do not cut, weld, drill, etc. containers, even empty. Sudden release of hot organic chemical vapors or mists from process equipment operating at elevated temperature and pressure, or sudden ingress of air into vacuum equipment, may result in ignitions without any obvious ignition sources. Published "autoignition" or "ignition" temperatures cannot be treated as safe operating temperatures in chemical processes without analysis of the actual process conditions. Use of this product in elevated temperature applications should be thoroughly evaluated to assure safe operating conditions. Store away from excessive heat and oxidizers. -
Disposal information
Dispose of product in accordance with all local, state/provincial and federal regulations. -
California Prop. 65 Warning
This product contains the following chemicals regulated under California Proposition 65: Ethylene Glycol CAS No. 000107-21-1, developmental
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First Aid
Eye Contact: Immediately flush eyes with large amounts of water for 15 minutes. Get medical attention if irritation persists.Skin Contact: Remove contaminated clothing. Immediately wash contacted area thoroughly with soap and water. If irritation persists, get medical attention.Inhalation: Remove the victim to fresh air. If breathing has stopped administer artificial respiration. If breathing is difficult, have medical personnel administer oxygen. Get medical attention.Ingestion: Seek immediate medical attention. Immediately call local poison control center or go to an emergency department. Never give anything by mouth to or induce vomiting in an unconscious or drowsy person.Notes to Physician: The principal toxic effects of ethylene glycol, when swallowed, are kidney damage and metabolic acidosis. The combination of metabolic acidosis, an osmol gap and oxalate crystals in the urine is evidence of ethylene glycol poisoning. Pulmonary edema with hypoxemia has been described in a number of patients following poisoning with ethylene glycol. Respiratory support with mechanical ventilation may be required. There may be cranial nerve involvement in the late stages of toxicity from swallowed ethylene glycol. In particular, effects have been reported involving the seventh, eighth, and ninth cranial nerves, presenting with bilateral facial paralysis, diminished hearing and dysphagia. Ethanol is antidotal and its early administration may block the formation of nephrotoxic metabolites of ethylene glycol in the liver. The objective is to rapidly achieve and maintain a blood ethanol level of approximately 100 mg/dl by giving a loading dose of ethanol followed by a maintenance dose. Intravenous administration of ethanol is the preferred route. Ethanol blood levels should be checked frequently. Hemodialysis may be required. 4-Methyl pyrazole (Fomepizole), a potent inhibitor of alcohol dehydrogenase, has been used therapeutically to decrease the metabolic consequences of ethylene glycol poisoning. Fomepizole is easier to use clinically than ethanol, does not cause CNS depression or hypoglycemia and requires less monitoring than ethanol. Additional therapeutic modalities which may decrease the adverse consequences of ethylene glycol metabolism are the administration of both thiamine and pyridoxine. As there are complicated and serious overdoses, we recommend you consult with the toxicologists at your poison control center.
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UN Global Harmonization Classification
